Article

A widespread internal brain state for fentanyl withdrawal

2026-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Opioid addiction is characterized by escalating drug use, driven in part by negative reinforcement from withdrawal, but the neural processes linking withdrawal to increased drug-taking remain poorly understood. Here, we use multisite local field potential recordings and interpretable machine learning to identify large-scale brain networks engaged by repeated opioid exposure and withdrawal. After...

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Literature Corpus work: 9e25f18f-d3b3-58e2-8522-4d0c87bbf06b
DOI: 10.64898/2026.05.04.722791

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