Article

Chronic oral fentanyl consumption produces dynamic behavioral adaptations during abstinence in female mice

2026-07-30

Abstract excerpt

<h4>Rationale</h4> The opioid epidemic continues to be driven by synthetic opioids, particularly fentanyl, yet the long-term behavioral manifestations of withdrawal remain poorly characterized. Women exhibit unique vulnerabilities to opioid use disorder, including greater susceptibility to withdrawal-related symptoms and relapse, suggesting that defining the behavioral adaptations that emerge during prolonged fen...

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Literature Corpus work: 148ebc05-6e78-5907-8aaf-31fbe43cc573
DOI: 10.64898/2026.07.27.741002

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