Article

A multi-symptomatic model of heroin use disorder in rats reveals distinct behavioral profiles and neuronal correlates of heroin vulnerability versus resiliency

2024-02-23

Abstract excerpt

<h4>Objective</h4> The behavioral and diagnostic heterogeneity within human opioid use disorder (OUD) diagnosis is not readily captured in current animal models, limiting translational relevance of the mechanistic research that is conducted in experimental animals. We hypothesize that a non-linear clustering of OUD-like behavioral traits will capture population heterogeneity and yield subpopulations of OUD vulner...

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Literature Corpus work: 721344b6-9948-5480-9565-516a97605db1
DOI: 10.1101/2024.02.22.581440

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