Article

Central amygdalar PKCδ neurons mediate fentanyl withdrawal

2025-02-24

Abstract excerpt

<h4>ABSTRACT</h4> Aversion to opioid withdrawal is a significant barrier to achieving lasting opioid abstinence. The central amygdala (CeA), a key brain region for pain, threat-detection, autonomic engagement, and valence assignment, is active during opioid withdrawal. However, the role of molecularly distinct CeA neural populations in withdrawal remains underexplored. Here, we investigated the activity dynamics,...

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Literature Corpus work: 410851bf-b0eb-5680-883b-fc2c46a2e97a
DOI: 10.1101/2025.02.21.639538

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