Article

Cell-type-specific mapping of enhancers and target genes from single-cell multimodal data

2024-09-26

Abstract excerpt

Mapping enhancers and target genes in disease-related cell types has provided critical insights into the functional mechanisms of genetic variants identified by genomewide association studies (GWAS). However, most existing analyses rely on bulk data or cultured cell lines, which may fail to identify cell-type-specific enhancers and target genes. Recently, single-cell multimodal data measuring both gene expression...

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Literature Corpus work: 9e1a68a4-0249-5c28-bc93-00df7de37e29
DOI: 10.1101/2024.09.24.614814

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