Article

Vessel Organoids Reveal FOXF1 Variant-Specific Regulation of Mesoderm and Capillary Development

2026-07-14

Abstract excerpt

<h4>SUMMARY</h4> How allelic variants in lineage-regulating transcription factors drive diverging human developmental outcomes remains poorly understood. This is partly due to the lack of human model systems. Here, we used vessel organoids from human induced pluripotent stem cells (hiPSCs) to resolve variant-specific functions of Forkhead Box F1 (FOXF1), a critical regulator of mesoderm and vascular development....

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Literature Corpus work: 9e195575-cd6d-5647-8e76-923d906fe38b
DOI: 10.64898/2026.07.12.737936

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