Article
Harnessing iPSCs, 3D organoids, and multiomics to model rare vascular diseases: Emerging new approach methodologies.
Vascular medicine (London, England) - 1 Feb 2026
Liu Lu, Wu David, Tsao Philip S, Leeper Nicholas J, Sayed Nazish
Abstract excerpt
Rare vascular diseases are a diverse group of life-threatening conditions defined by their low prevalence but profound impact on patient morbidity and quality of life. Diagnosing these disorders remains a significant clinical challenge due to their genetic heterogeneity, overlapping phenotypes, and limited patient populations. As such, the development of robust and human-relevant disease models is critical for...
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