Article

A Microphysiological HHT-on-a-Chip Platform Recapitulates Patient Vascular Lesions

2024-06-18

Abstract excerpt

<title>Abstract</title> <p>Hereditary Hemorrhagic Telangiectasia (HHT) is a rare congenital disease in which fragile vascular malformations (VM) – including small telangiectasias and large arteriovenous malformations (AVMs) – focally develop in multiple organs. There are few treatment options and no cure for HHT. Most HHT patients are heterozygous for loss-of-function mutations affecting Endoglin (ENG) or Alk1 (A...

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Literature Corpus work: f284a2b5-5f09-5574-a645-5aac16c97709
DOI: 10.21203/rs.3.rs-4578507/v1

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