Article

Molecular and structural remodeling of stress granules in slowly and rapidly progressive Alzheimer’s disease

2025-07-24

Abstract excerpt

Stress granules (SGs) are dynamic ribonucleoprotein condensates that modulate RNA metabolism during cellular stress. Although SG dysfunction has been increasingly linked to neurodegenerative diseases, their structural and molecular remodeling in Alzheimer’s disease (AD), particularly rapidly progressive AD (rpAD), remains poorly understood. Here, we present a comprehensive multi-omics characterization of SGs from...

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Literature Corpus work: 9e1151ca-7fd3-5456-830d-494ec4d539be
DOI: 10.1101/2025.07.20.665556

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