Article
Differential interactome mapping of aggregation prone/prion-like proteins under stress: novel links to stress granule biology
1 Dec 2023
Abstract excerpt
BACKGROUND: Aberrant stress granules (SGs) are emerging as prime suspects in the nucleation of toxic protein aggregates. Understanding the molecular networks linked with aggregation-prone proteins (prion protein, synuclein, and tau) under stressful environments is crucial to understand pathophysiological cascades associated with these proteins. METHODS: We characterized and validated oxidative stress-induced...
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