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Targeting stress granules in neurodegenerative diseases: A focus on biological function and dynamics disorders

15 Nov 2023

Abstract excerpt

Stress granules (SGs) are membraneless organelles formed by eukaryotic cells in response to stress to promote cell survival through their pleiotropic cytoprotective effects. SGs recruit a variety of components to enhance their physiological function, and play a critical role in the propagation of pathological proteins, a key factor in neurodegeneration. Recent advances indicate that SG dynamic disorders...

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PMID: 37966813
DOI: 10.1002/biof.2017

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