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Article

Role of stress granules and RNA-binding proteins in neurodegeneration: a mini-review.

Gerontology - 1 Jan 2013

Vanderweyde Tara, Youmans Katie, Liu-Yesucevitz Liqun, Wolozin Benjamin

Abstract excerpt

The eukaryotic stress response involves translational suppression of non-housekeeping proteins and the sequestration of unnecessary mRNA transcripts into stress granules (SGs). This process is dependent on mRNA-binding proteins (RBPs) that interact with capped mRNA transcripts through RNA recognition motifs, and exhibit reversible aggregation through hydrophobic polyglycine domains, some of which are homologous...

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Identifiers

PMID: 24008580
DOI: 10.1159/000354170
PMCID: PMC3863624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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