Article

Telomere-to-telomere assembly by preserving contained reads

2023-11-11

Abstract excerpt

Automated telomere-to-telomere (T2T) de novo assembly of diploid and polyploid genomes remains a formidable task. A string graph is a commonly used assembly graph representation in the overlap-based algorithms. The string graph formulation employs graph simplification heuristics, which drastically reduce the count of vertices and edges. One of these heuristics involves removing the reads contained in longer reads...

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Literature Corpus work: 9e0a873d-b9ab-57bd-b117-3cfe9fba07d7
DOI: 10.1101/2023.11.07.565066

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