Article

LJA: Assembling Long and Accurate Reads Using Multiplex de Bruijn Graphs

2020-12-11

Abstract excerpt

Although most existing genome assemblers are based on the de Bruijn graphs, it remains unclear how to construct these graphs for large genomes and large k -mer sizes. This algorithmic challenge has become particularly important with the emergence of long high-fidelity (HiFi) reads that were recently utilized to generate a semi-manual telomere-to-telomere assembly of the human genome and to get a glimpse into biom...

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Literature Corpus work: 5b0d8cf1-2802-5353-84b7-87dd4c346867
DOI: 10.1101/2020.12.10.420448

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