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NPGREAT: Assembly of the human subtelomere regions with the use of ultralong Nanopore reads and Linked-Reads

2021-11-19

Abstract excerpt

<h4>Background: </h4> Human subtelomeric DNA regulates the length and stability of adjacent telomeres that are critical for cellular function, and contains many gene/pseudogene families. Large evolutionarily recent segmental duplications and associated structural variation in human subtelomeres has made complete sequencing and assembly of these regions difficult to impossible for many loci, complicating or preclud...

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Literature Corpus work
0f536e27-2b97-58c6-8cea-80cebf5bae87
DOI
10.21203/rs.3.rs-1080088/v1
Open publication

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NPGREAT: Assembly of the human subtelomere regions with the use of ultralong Nanopore reads and Linked-ReadsDOI 10.21203/rs.3.rs-1080088/v1
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