Article

Gapless assembly of complete human and plant chromosomes using only nanopore sequencing

2024-03-17

Abstract excerpt

The combination of ultra-long Oxford Nanopore (ONT) sequencing reads with long, accurate PacBio HiFi reads has enabled the completion of a human genome and spurred similar efforts to complete the genomes of many other species. However, this approach for complete, "telomere-to-telomere" genome assembly relies on multiple sequencing platforms, limiting its accessibility. ONT "Duplex" sequencing reads, where both str...

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Literature Corpus work: 293abc91-f628-5881-8736-f14fac16d520
DOI: 10.1101/2024.03.15.585294

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