Article

Telomere-to-Telomere Phased Genome Assembly Using HERRO-Corrected Simplex Nanopore Reads

2024-05-21

Abstract excerpt

Telomere-to-telomere phased assemblies have become the norm in genomics. To achieve these for diploid and even polyploid genomes, the contemporary approach involves a combination of two long-read sequencing technologies: high-accuracy long reads, e.g. Pacific Biosciences (PacBio) HiFi or Oxford Nanopore (ONT) 'Duplex' reads, and ultra-long ONT 'Simplex' reads. Using two different technologies increases the cost an...

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Literature Corpus work: 1cba4f21-ea45-5eac-9467-bd6f31963cfb
DOI: 10.1101/2024.05.18.594796

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