Article

Verkko: telomere-to-telomere assembly of diploid chromosomes

2022-06-26

Abstract excerpt

The Telomere-to-Telomere consortium recently assembled the first truly complete sequence of a human genome. To resolve the most complex repeats, this project relied on manual integration of ultra-long Oxford Nanopore sequencing reads with a high-resolution assembly graph built from long, accurate PacBio HiFi reads. We have improved and automated this strategy in Verkko, an iterative, graph-based pipeline for assem...

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Literature Corpus work: 4bf92824-7b50-5792-814d-c5df6266ba54
DOI: 10.1101/2022.06.24.497523

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