Article

Surveying the Genomic Landscape of Mantle Cell Lymphoma Indicates the Importance of Multimodal Genomic and Transcriptomic Exploration

2026-07-29

Abstract excerpt

Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin lymphoma characterized by heterogeneous clinical courses despite a common pathobiological initiating event. In this work we explore the genomic variants that characterize MCL and integrate transcriptomic data to comprehensively describe MCL biology. We performed whole exome sequencing (WES) on 28 tumor-normal pairs (lymph node and skin, respectively), as well as w...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9dbea3b7-767f-5120-9dc6-91eba1546ade
DOI: 10.64898/2026.07.25.26358867

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Surveying the Genomic Landscape of Mantle Cell Lymphoma Indicates the Importance of Multimodal Genomic and Transcriptomic ExplorationDOI 10.64898/2026.07.25.26358867Read

Landscape of somatic mutations and clonal evolution in mantle cell lymphoma.Semantic proximity Read

The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells.Semantic proximity Read

Genomic landscape and prognostic analysis of mantle cell lymphoma.Semantic proximity Read

Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma.Semantic proximity Read

Coding and noncoding drivers of mantle cell lymphoma identified through exome and genome sequencing.Semantic proximity Read

Coding and non-coding drivers of mantle cell lymphoma identified through exome and genome sequencingSemantic proximity Read

Genetic mutations and features of mantle cell lymphoma: a systematic review and meta-analysis.Semantic proximity Read

Genomic and epigenomic insights into the origin, pathogenesis, and clinical behavior of mantle cell lymphoma subtypes.Semantic proximity Read

Comprehensive genetic analysis by targeted sequencing identifies risk factors and predicts patient outcome in Mantle Cell Lymphoma: results from the EU-MCL network trials.Semantic proximity Read

Comprehensive genetic analysis by targeted sequencing identifies risk factors and predicts patient outcome in Mantle Cell Lymphoma: results from the EU-MCL network trialsSemantic proximity Read

Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomesSemantic proximity Read

Targeted genomic investigations in a population-based cohort of mantle cell lymphoma reveal novel clinically relevant targets.Semantic proximity Read