Article
Somatic Mutations Render Human Exome and Pathogen DNA more Similar
2018-05-14
Abstract excerpt
Immunotherapy has recently shown important clinical successes in a substantial number of oncology indications. Additionally, the tumor somatic mutation load has been shown to associate with response to these therapeutic agents, and specific mutational signatures are hypothesized to improve this association, including signatures related to pathogen insults. We sought to study in silico the validity of these observa...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 9dbbbdbe-2e1d-5049-8356-e4e0e1518308
- DOI
- 10.1101/322016