Mutagenesis by Microbe: the Role of the Microbiota in Shaping the Cancer Genome.

Abstract excerpt

Cancers arise through the process of somatic evolution fueled by the inception of somatic mutations. We lack a complete understanding of the sources of these somatic mutations. Humans host a vast repertoire of microbes collectively known as the microbiota. The microbiota plays a role in altering the tumor microenvironment and proliferation. In addition, microbes have been shown to elicit DNA damage which provides...

Topics

Join the communities discussing this publication.

• Bacterial Infections
• DNA Damage
• Genome, Human
• Genomics
• Host Microbial Interactions