Article

MALDI-TOF mass spectrometry and proteomics as phenotypic screening tools for anti-inflammatory drugs

2025-12-03

Abstract excerpt

Phenotypic screening is a powerful technology to discover drug candidates in physiologically relevant systems without prior knowledge of molecular targets; however, mass spectrometry (MS) remains underutilised as readout strategy. In this proof-of-concept study, we developed and evaluated two complementary MS-based phenotypic screening approaches to identify anti-inflammatory compounds in human induced pluripotent...

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Literature Corpus work: 9db4b237-03ef-52b7-b132-517c3519298b
DOI: 10.64898/2025.12.01.691706

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