Article

Integration of imaging modalities with lipidomic characterization to investigate MSCs potency metrics

2022-05-26

Abstract excerpt

Mesenchymal stem cells (MSCs) are widely used as therapeutics targets for numerous autoimmune diseases. However, MSC therapies have had limited success so far in clinical trials, mainly being heterogenous population it is difficult to determine MSCs efficiencies. It is critical to understand internal signaling of individual MSCs population that directly affect the cell phenotype. Lipid signaling is closely associa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 385bf6a1-cd46-5908-991a-444ce1bf48e7
DOI: 10.1101/2022.05.25.493259

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Integration of imaging modalities with lipidomic characterization to investigate MSCs potency metricsDOI 10.1101/2022.05.25.493259Read

Characterizing Human Mesenchymal Stromal Cells Immune Modulatory Potency Using Targeted Lipidomic Profiling of SphingolipidsSemantic proximity Read

Emerging role of lipid metabolism alterations in Cancer stem cells.Semantic proximity Read

Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context.Semantic proximity Read

Sphingomyelinase Licensing of Mesenchymal Stromal Cells Alters Lipid and Protein Metabolites for ImmunomodulationSemantic proximity Read

Multiomics characterization of mesenchymal stromal cells cultured in monolayer and as aggregatesSemantic proximity Read

Biomolecular phenotyping and heterogeneity assessment of mesenchymal stromal cells using label-free Raman spectroscopy.Semantic proximity Read

Metabolomic Applications in Stem Cell Research: a ReviewSemantic proximity Read

Cardiolipin Remodeling as a Regulatory Switch in Osteogenesis: Insights from Multimodal Metabolic Imaging and Molecular ProfilingSemantic proximity Read

Research advances in Raman imaging of single-cell phenotypes in fatty acid metabolism in cancers.Semantic proximity Read

Nanomaterial-Based Repurposing of Macrophage Metabolism and Its ApplicationsSemantic proximity Read

Global signatures of the human mesenchymal stromal cell secretome: A comparative proteomic analysis of iPSC and tissue-derived MSC secretomes before and after inflammatory licensingSemantic proximity Read

Random forest and live single-cell metabolomics reveal metabolic profiles of human macrophages upon polarization.Semantic proximity Read