dia-PASEF Enables Rapid Profiling of the Human Secretome for Deeper Insights into Cellular Dynamics and Inflammatory Mechanisms

Abstract excerpt

Protein secretion is a fundamental mechanism for cellular coordination and signalling, with its dysregulation leading to widespread physiological dysfunction and disease. Immunoassay formats that utilise secondary antibody readouts are the current gold standard for measuring secreted proteins, offering high specificity and sensitivity, but relying on predefined protein panels that constrain the discovery of novel...

Topics

Open a Topic to create a Post that cites this publication.

• Asthma and respiratory diseases
• Cell Adhesion Molecules Research
• Infectious Diseases and Tuberculosis
• Mast cells and histamine
• Mycobacterium research and diagnosis
• Pneumocystis jirovecii pneumonia detection and treatment
• Tuberculosis Research and Epidemiology
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

9dcd9c6a-aa7d-5e58-93a5-9b995830d0a3

DOI

10.64898/2026.01.07.698113