Article

The development of ToF-SIMS for in-situ glycosaminoglycan analysis

2026-05-08

Abstract excerpt

Glycosaminoglycans (GAGs) are linear polysaccharides with essential roles in a myriad of biological processes. Despite their biological importance, methods to determine both spatial and compositional information is limited. Time-of-flight secondary ion mass spectrometry (ToF-SIMS) provides spatially resolved compositional information of biological molecules without enzymatic digestion or label incorporation, enabl...

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Literature Corpus work: f7675d76-acaa-5964-a2a3-2e675d3258b3
DOI: 10.64898/2026.05.06.723150

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