Article

Overexpression of HNF4α enhances umbilical cord mesenchymal stem cell function to treat acute liver failure in mice through macrophage polarization

2020-11-05

Abstract excerpt

<h4>Background: </h4> and aim: Advances in research on stem cell therapy provide new feasible solutions for acute liver failure (ALF) treatment. Recent studies have demonstrated that the expression of hepatocyte nuclear factor 4α (HNF4α) reset within the damaged hepatocytes can restore normal physiological function. This study aimed to determine the role of human umbilical cord mesenchymal stem cells (HuMSCs) over...

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Literature Corpus work: 9d97de18-a19c-55e5-9064-17ca3f7acfb0
DOI: 10.21203/rs.3.rs-26740/v2

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