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HNF-4α determines hepatic differentiation of human mesenchymal stem cells from bone marrow

1 Jan 2010

Abstract excerpt

AIM: To investigate the differentiation status and key factors to facilitate hepatic differentiation of human bone-marrow-derived mesenchymal stem cells (MSCs). METHODS: Human MSCs derived from bone marrow were induced into hepatocyte-like cells following a previously published protocol. The differentiation status of the hepatocyte-like cells was compared with various human hepatoma cell lines. Overexpression of...

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PMID: 20976847
DOI: 10.3748/wjg.v16.i40.5092

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