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Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells Alleviate Acetaminophen-induced Acute Liver Failure Through Activating ERK and IGF-1R/PI3K/AKT Signaling Pathways

2020-09-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Human umbilical cord mesenchymal stem cells (hUCMSCs) transplantation has been proposed as a promising therapeutic approach for treating acute liver failure (ALF), but its application is limited by immune rejection and tumor formation. Exosomes contain various bioactive cargos including mRNA, microRNA, and protein that can alter the cellular enviroment to enhanc...

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Literature Corpus work
edff23f3-e8b2-5766-a7b0-bd1238569e72
DOI
10.21203/rs.3.rs-74818/v1
Open publication

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Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells Alleviate Acetaminophen-induced Acute Liver Failure Through Activating ERK and IGF-1R/PI3K/AKT Signaling PathwaysDOI 10.21203/rs.3.rs-74818/v1
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