Article
Arginine methylation promotes siRNA-binding specificity for a spermatogenesis-specific isoform of the Argonaute protein CSR-1
2020-06-09
Abstract excerpt
<h4>Summary</h4> CSR-1 is an essential Argonaute protein that binds to a subclass of 22G-RNAs targeting most germline-expressed genes. Here we show that the two isoforms of CSR-1 have distinct expression patterns; CSR-1B is ubiquitously expressed throughout the germline and during all stages of development while CSR-1A expression is restricted to germ cells undergoing spermatogenesis. Furthermore, CSR-1A associat...
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Identifiers and source
- Literature Corpus work
- 9d86f8b8-f822-50f2-ab00-c4e80d2755ec
- DOI
- 10.1101/2020.06.08.134908
