Article

A pathway to produce non-coding piRNAs from endogenous protein-coding regions supports Drosophila spermatogenesis

2022-10-03

Abstract excerpt

<h4>Summary</h4> PIWI-interacting (pi)RNA pathways control transposable elements (TEs) and endogenous genes in animal gonads, playing important roles in gamete formation. Here, we report a mechanism by which endo genous protein-coding regions, that normally provide their sequences for translation, serve as origins of non-coding piRNA biogenesis in Drosophila melanogaster testes. The products, namely endo-piRNAs...

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Identifiers and source

Literature Corpus work: 1081162c-9524-5ffd-8fb5-f9531c431b72
DOI: 10.1101/2022.10.02.510544

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