Article

A family of <i>C. elegans</i> VASA homologs control Argonaute pathway specificity and promote transgenerational silencing

2022-01-18

Abstract excerpt

<h4>ABSTRACT</h4> Germline Argonautes direct transcriptome surveillance within peri-nuclear membraneless organelles called nuage. In C. elegans, a family of Vasa-related Germ Line Helicase (GLH) proteins localize in, and promote the formation of nuage called P granules. Previous studies have implicated GLH proteins in inherited silencing but direct roles in amplification of small RNAs, or in target mRNA or Argon...

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Literature Corpus work: 80b78618-0529-5b88-93b4-1b698a2d4fec
DOI: 10.1101/2022.01.18.476504

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