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A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin

2018-04-02

Abstract excerpt

Significance Influenza is a contagious and sometimes lethal disease of the human respiratory tract. Current preventative measures include annual vaccination and a limited number of antiviral drugs. However, the effectiveness of the seasonal vaccine is unpredictable, and resistance has been developing to all approved drugs. Therefore, novel influenza therapeutics with new targets and mechanisms are essential to pro...

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Literature Corpus work
9cf5122d-3471-5959-851b-b446e5707f7d
DOI
10.1073/pnas.1801999115
Open publication

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A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutininDOI 10.1073/pnas.1801999115
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