Learning from structure-based drug design and new antivirals targeting the ribonucleoprotein complex for the treatment of influenza

Abstract excerpt

INTRODUCTION: Influenza viruses are a threat to human health. There are presently only two methods for treating influenza: vaccines, which require yearly updates, and two classes of antivirals that suffer with the problem of resistance by current human influenza viruses; this is especially the case with amantadine and rimantadine. Consequently, there is an urgent need for the development of new antivirals with...

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