Article
Influenza Neuraminidase Characteristics and Potential as a Vaccine Target.
Frontiers in immunology - 1 Jan 2021
Creytens Sarah, Pascha Mirte N, Ballegeer Marlies, Saelens Xavier, de Haan Cornelis A M
Abstract excerpt
Neuraminidase of influenza A and B viruses plays a critical role in the virus life cycle and is an important target of the host immune system. Here, we highlight the current understanding of influenza neuraminidase structure, function, antigenicity, immunogenicity, and immune protective potential. Neuraminidase inhibiting antibodies have been recognized as correlates of protection against disease caused by...
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