Article
Antivirals Targeting the Surface Glycoproteins of Influenza Virus: Mechanisms of Action and Resistance
6 Apr 2021
Abstract excerpt
Hemagglutinin and neuraminidase, which constitute the glycoprotein spikes expressed on the surface of influenza A and B viruses, are the most exposed parts of the virus and play critical roles in the viral lifecycle. As such, they make prominent targets for the immune response and antiviral drugs. Neuraminidase inhibitors, particularly oseltamivir, constitute the most commonly used antivirals against influenza...
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