Article

The prevalence of Lynch syndrome (DNA mismatch repair protein deficiency) in patients with primary localized prostate cancer

2023-01-12

Abstract excerpt

<h4>Background: </h4> Prostate cancer is one of the most heritable human cancers. Lynch syndrome is an autosomal dominant inheritance caused by germline mutations in DNA mismatch repair (MMR) genes, which are also associated with an increased incidence of prostate cancer. However, prostate cancer has not been defined as a Lynch syndrome-associated cancer. The proportion of Lynch syndrome patients in primary prosta...

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Literature Corpus work: 9cb28dec-1d63-5d2e-b759-6951166c32ac
DOI: 10.21203/rs.3.rs-2458921/v1

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