Article
Elevated risk of prostate cancer among men with Lynch syndrome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 May 2013
Raymond Victoria M, Mukherjee Bhramar, Wang Fei, Huang Shu-Chen, Stoffel Elena M, Kastrinos Fay, Syngal Sapna, Cooney Kathleen A, Gruber Stephen B
Abstract excerpt
PURPOSE: Prostate cancer has been described as a component tumor of Lynch syndrome (LS), with tumors obtained from mutation carriers demonstrating the DNA mismatch repair deficiency phenotype. Previous studies quantifying prostate cancer risk in LS have provided conflicting results. METHODS: We examined cancer histories of probands and their first- through fourth-degree relatives for 198 independent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
