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High-content phenotypic analysis of <i>a C. elegans</i> recombinant inbred population identifies genetic and molecular regulators of lifespan

2024-01-16

Abstract excerpt

Lifespan is influenced by complex interactions between genetic and environmental factors. Studying those factors in model organisms of a single genetic background limits their translational value for humans. Here, we mapped lifespan determinants in 85 genetically diverse C. elegans recombinant intercross advanced inbred lines (RIAILs). We assessed molecular profiles – transcriptome, proteome, and lipidome – and l...

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Literature Corpus work
e70eb027-f3cc-5b56-a577-59b8d8e7cb22
DOI
10.1101/2024.01.15.575638
Open publication

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High-content phenotypic analysis of <i>a C. elegans</i> recombinant inbred population identifies genetic and molecular regulators of lifespanDOI 10.1101/2024.01.15.575638
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