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Multi-omics analysis identifies essential regulators of mitochondrial stress response in two wild-type <i>C. elegans</i> strains

2021-07-20

Abstract excerpt

The mitochondrial unfolded protein response (UPRmt) is a promising pharmacological target for aging and age-related diseases. However, the integrative analysis of the impact of UPRmt activation on different layers of signaling in animals with a different genetic background is lacking. In this study, we applied systems approaches to investigate the effect of UPRmt induced by administering doxycycline (Dox) on trans...

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Literature Corpus work
2aebcc80-a07f-56d6-a20b-1e1de24fac31
DOI
10.1101/2021.07.20.453059
Open publication

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Multi-omics analysis identifies essential regulators of mitochondrial stress response in two wild-type <i>C. elegans</i> strainsDOI 10.1101/2021.07.20.453059
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