Article

PARTAGE: Parallel analysis of replication timing and gene expression

2025-09-06

Abstract excerpt

The human genome is partitioned into functional compartments that replicate at specific times during the S-phase. This temporal program, referred to as replication timing (RT), is co-regulated with the 3D genome organization, is cell type-specific, and changes during development in coordination with gene expression. Moreover, RT alterations are linked to abnormal gene expression, genome instability, and structural...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9c9ff6e1-d835-5ee8-9be7-3225255575fd
DOI: 10.1101/2025.09.02.673838

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

PARTAGE: Parallel analysis of replication timing and gene expressionDOI 10.1101/2025.09.02.673838Read

Repli-seq: genome-wide analysis of replication timing by next-generation sequencingSemantic proximity Read

Optimized Repli-seq: Improved DNA Replication Timing Analysis by Next-Generation SequencingSemantic proximity Read

RT States: systematic annotation of the human genome using cell type-specific replication timing programsSemantic proximity Read

Sequencing newly replicated DNA reveals widespread plasticity in human replication timingSemantic proximity Read

Replication Timing Networks: a novel class of gene regulatory networksSemantic proximity Read

The Genetic Architecture of DNA Replication Timing in Human Pluripotent Stem CellsSemantic proximity Read

Concert: Genome-wide prediction of sequence elements that modulate DNA replication timingSemantic proximity Read

Comprehensive analysis of DNA replication timing in genetic diseases and gene knockouts identifies <i>MCM10</i> as a novel regulator of the replication programSemantic proximity Read

DNA replication timing and long-range DNA interactions predict mutational landscapes of cancer genomes.Semantic proximity Read

Replication Stress, Genomic Instability, and Replication Timing: A Complex Relationship.Semantic proximity Read

A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reveals the cellular and molecular impact of chromosome instabilitySemantic proximity Read

Coalescing single-cell genomes and transcriptomes to decode breast cancer progression.Semantic proximity Read