Article

Concert: Genome-wide prediction of sequence elements that modulate DNA replication timing

2022-04-22

Abstract excerpt

Proper control of replication timing (RT) is of vital importance to maintain genome and epigenome integrity. However, the genome-wide sequence determinants regulating RT remain unclear. Here, we develop a new machine learning method, named C oncert , to simultaneously predict RT from sequence features and identify RT-modulating sequence elements in a genome-wide manner. C oncert integrates two functionally coope...

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Literature Corpus work: fc8a6a1a-f74a-5bc2-be49-2e7f8043482c
DOI: 10.1101/2022.04.21.488684

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