Article

The metabolic and redox signaling of the nucleoredoxin-like 2 gene supports brain function

2022-12-05

Abstract excerpt

<title>Abstract</title> <p>The nucleoredoxin genes <italic>NXNL2</italic> encodes by alternative splicing for a secreted truncated thioredoxin that mediates neuronal survival and a thioredoxin enzyme that regulates the phosphorylation of TAU. Behavioral analyses of young <italic>Nxnl2</italic><sup>-/-</sup> mice demonstrate that this gene is involved in regulating of brain functions and is essential for learning...

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Literature Corpus work: 9c9a9601-44b5-5e34-8147-dae6ced1a91b
DOI: 10.21203/rs.3.pex-1558/v1

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