Article

Transcriptomic Issues with Animal Models for Neurological Diseases

2026-06-16

Abstract excerpt

Despite ethical constraints and strict oversight by local Institutional Animal Care and Use Committees, animal models still permit molecular investigations that would never be acceptable to humans. Nevertheless, experimental outcomes depend on species, strain, sex, age, hormonal status, diet, exposure to hypoxia, toxins, radiation, external stimuli, stress, and even housing conditions. Further complications stem f...

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Literature Corpus work: c7d7c696-ff82-572b-87af-16bf3cee4bbb
DOI: 10.20944/preprints202606.1218.v1

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