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Article

Silencing of the ADNP‐family member, ADNP2, results in changes in cellular viability under oxidative stress

6 Dec 2007

Abstract excerpt

Activity-dependent neuroprotective protein (ADNP) 2 (KIAA0863; ZNF508) gene, a homeobox-profile containing gene, was identified in a screen for homologous proteins to ADNP. The human ADNP2 contains 1131 amino acid residues with a molecular weight of 122.8 KDa. In silico analysis indicated that ortholgs to ADNP2 exist in different phyla, suggesting that ADNP2 might be evolutionary conserved. Here, we began to...

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PMID: 18179478
DOI: 10.1111/j.1471-4159.2007.05173.x

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