Article

The toxic nature of murine amylin and the immune responsivity of pancreatic islet to conformational antibody in mice

2017-08-12

Abstract excerpt

<h4>ABSTRACT</h4> The human amylin is a pancreatic peptide hormone cosecreted with amylin and found in hyperhormonemic state along with insulin in subclinical diabetes. Amylin has been associated with the pathology of type 2 diabetes, particularly due to its ability to assembly into toxic oligomers and amyloid speciments. On the other hand, some variants such as murine amylin has been described as non amyloidogen...

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Literature Corpus work: 9c7d07c1-4747-5e8a-b495-e86256ebcf1a
DOI: 10.1101/175539

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