Article

Gene regulatory activity associated with PCOS revealed <i>DENND1A</i> -dependent testosterone production

2024-05-28

Abstract excerpt

Polycystic ovary syndrome (PCOS) is among the most common disorders affecting up to 15% of the menstruating population globally. It is the leading cause of anovulatory infertility and a major risk factor for type 2 diabetes. Elevated testosterone levels are a core endophenotype. Despite that prevalence, the underlying causes remain unknown. PCOS genome-wide association studies (GWAS) have reproducibly mapped a num...

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Literature Corpus work: 9c75287b-0f17-5f03-a776-4da3aa83a55b
DOI: 10.1101/2024.05.23.595551

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