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A conserved regulatory atlas reveals enhancers critical for mouse and human gonadal development

2026-07-13

Abstract excerpt

Differences of Sex Development (DSD) are congenital conditions where sex development is atypical. Like many other rare conditions, genetic diagnostic rates for DSD still sit below 50%. Unexplained cases may harbour disruptions in non-coding regulatory regions, which remain largely unexplored. Here, we integrate chromatin accessibility datasets from mouse and human embryonic gonads to construct a complete comparati...

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Literature Corpus work
021f8438-252d-52f5-ade5-ea8d6bfcfa89
DOI
10.64898/2026.07.09.26357422
Open publication

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A conserved regulatory atlas reveals enhancers critical for mouse and human gonadal developmentDOI 10.64898/2026.07.09.26357422
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