Article

Family-based quantitative trait meta-analysis implicates rare noncoding variants in <i>DENND1A</i> in pathogenesis of polycystic ovary syndrome

2018-11-04

Abstract excerpt

<h4>ABSTRACT</h4> Polycystic ovary syndrome (PCOS) is among the most common endocrine disorders of premenopausal women, affecting 5-15% of this population depending on the diagnostic criteria applied. It is characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. PCOS is a leading risk factor for type 2 diabetes in young women. PCOS is highly heritable, but only a small proporti...

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Literature Corpus work: 77e6b8f2-8c72-5703-9dee-e64e570c81f8
DOI: 10.1101/460972

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