Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sensitive and frequent identification of high avidity neo-epitope specific CD8 + T cells in immunotherapy-naive ovarian cancer

9 Mar 2018

Abstract excerpt

Abstract Immunotherapy directed against private tumor neo-antigens derived from non-synonymous somatic mutations is a promising strategy of personalized cancer immunotherapy. However, feasibility in low mutational load tumor types remains unknown. Comprehensive and deep analysis of circulating and tumor-infiltrating lymphocytes (TILs) for neo-epitope specific CD8 + T cells has allowed prompt identification of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to CAR-T cell therapy research
Share to Immunotherapy and Immune Responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29545564
DOI: 10.1038/s41467-018-03301-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sensitive and frequent identification of high avidity neo-epitope specific CD8 + T cells in immunotherapy-naive ovarian cancerPMID 29545564Read ↗

Harnessing tumor immunogenomics: Tumor neoantigens in ovarian cancer and beyond.Semantic proximity Read ↗

Impact of tumor heterogeneity and microenvironment in identifying neoantigens in a patient with ovarian cancer.Semantic proximity Read ↗

Low Mutation Burden in Ovarian Cancer May Limit the Utility of Neoantigen-Targeted Vaccines.Semantic proximity Read ↗

The Role of Neoantigens in Cancer ImmunotherapySemantic proximity Read ↗

Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoireSemantic proximity Read ↗

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma.Semantic proximity Read ↗

Utilizing immunogenomic approaches to prioritize targetable neoantigens for personalized cancer immunotherapy.Semantic proximity Read ↗

Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancersSemantic proximity Read ↗

Neoantigen-based cancer immunotherapySemantic proximity Read ↗

Advances and challenges in neoantigen prediction for cancer immunotherapySemantic proximity Read ↗

A functional identification platform reveals frequent, spontaneous neoantigen-specific T cell responses in patients with cancerSemantic proximity Read ↗

Tumor Immunity and Survival as a Function of Alternative Neopeptides in Human Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.