Article
New insights into tumor immunity revealed by the unique genetic and genomic aspects of ovarian cancer.
Current opinion in immunology - 1 Apr 2015
Nelson Brad H
Abstract excerpt
Ovarian cancer is a challenging disease that nonetheless provokes brisk, prognostically favorable immune responses in many patients. The biology of ovarian cancer offers unique insights into the factors that engender protective tumor immunity. Tumor-infiltrating lymphocyte (TIL) patterns range from CD8+ TIL alone to complex aggregates that additionally include CD4+ and CD20+ TIL. Patient survival rates increase...
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